74395
Fluka
Acridine Orange 10-nonyl bromide
BioChemika, for fluorescence, ≥90% (HPLC)
| Synonym: | 10-Nonylacridine orange bromide, 3,6-Bis(dimethylamino)-10-nonylacridinium bromide |
| CAS Number: | 75168-11-5 |
| Linear Formula: | C26H38BrN3 |
| Molecular Weight: | 472.50 |
| MDL number: | MFCD00467124 |
Description
| Application | Metachromatic dye useful as a mitochondrial probe in living cells. This dye has been used to analyze mitochondria by flow cytometry, characterize multidrug resistance, and measure changes in mitochondrial mass during apoptosis in rat thymocytes. |
| Other Notes | Fluorescent probe for the in situ study of mitochondria1,2 |
Properties
| grade | for fluorescence |
| product line | BioChemika |
| assay | ≥90% (HPLC) |
| fluorescence | λex 494 nm; λem 519 nm in methanol |
| mp | ≥250 °C(lit.) |
| solubility | DMSO: soluble |
| ethanol, DMSO: soluble | |
| ethanol: soluble | |
| methanol: soluble | |
| storage temp. | 2-8°C |
Safety
| Personal Protective Equipment | dust mask type N95 (US), Eyeshields, Gloves |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
References
| Cited Reference | 1. M.H. Ratinaud et al. Cytometry 9, 206, (1988) Abstract |
| 2. A. Maftah et al. FEBS Lett. 260, 236, (1990) Abstract | |
| reference | Cossarizza, A., Mitochondrial modifications during rat thymocyte apoptosis: a study at the single cell level. Exp. Cell Res. 214, 323, (1994) |
| Kessel, D., Characterization of multidrug resistance by fluorescent dyes. Cancer Res. 51, 4665, (1991) |
